Echinaforce drops
Echinaforce drops (Echinacea) is a popular herbal treatment and dietary supplement promoted as a self-care remedy for the common cold. This purple coneflower, part of the daisy family and native to North America, use in Native American medicines. Three species thought to boost the immune system—Echinacea purpurea, Echinacea angustifolia, and Echinacea pallida—are used in herbal supplements, extracts, and teas. But do echinacea’s potential anti-inflammatory and antibiotic health benefits really prevent or shorten the duration of the common cold?
Function
Echinacea Echinaforce drops has been studied extensively for treatment of the common cold and upper respiratory tract infections and may be effective in reducing the duration and severity of cold symptoms. Best known as an immunostimulant, Echinacea modulates the activation of JNK, p38-MAPK, and NF-kB pathways and inhibits inflammation by suppressing the expression of ICAM-1, fibronectin, and platelet activating factor receptor.
E. purpurea extract stimulates phagocytic activity and enhances TNF-a, IL-1, and IFN-B, increasing cytokine production.
The roots of echinacea contain alkylamides. Which activate cannabinoid receptor type 2, IL-10, and PPARy and inhibit TNF-a, boosting anti-inflammatory and immunomodulatory responses.
Echinaforce drops benefit?
While anti-inflammatory, antiviral, and antimicrobial effects have demonstrat in several clinical trials, the evidence for therapeutic efficacy is unclear. Randomized, double-blind, placebo-controlled trials have demonstrated that echinacea inhibits virally confirmed colds and virus infections. Preventive effects were seen to increase with adherence and compliance to the therapy protocol in these studies. A recent meta-analysis indicated that echinaforce modulation of the immune system. Through antiviral and anti-inflammatory effects lowers the risk of recurrences and complications of respiratory tract infection. A systematic review of studies showed that the plant may lower the risk of developing colds by more than 50% and shorten the duration of colds by 1.5 days.
Daily requirements and dietary sources
It is commercially available as tablets, extracts, juices, and teas. Suggested dosages vary depending on the preparation. A large clinical trial established efficacy of echinacea for prevention of colds with dosages of 2,400 mg per day for 4 months. During the acute stage of a cold, the recommended dosage was 4,000 mg per day.
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